CYP46A4P

Across TCGA patient cohorts, CYP46A4P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,477 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYP46A4P-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Neuron projection organization, and Notch signaling pathway. Each is linked with CYP46A4P in more than 14 cancer types. Because this analysis shows association rather than direction, both CYP46A4P-to-partner and partner-to-CYP46A4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by CYP46A4P-low versus CYP46A4P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP46A4P→partner) and Y-score (partner→CYP46A4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of intracellular protein transport →	+0.077	+0.175	<.001	<.001	3	15
STAD	Neuron projection organization →	+0.048	+0.158	<.001	<.001	3	14
STAD	Notch signaling pathway →	+0.063	+0.176	<.001	<.001	3	14
DLBC	Postsynapse organization →	+0.044	+0.199	<.001	<.001	3	14
STAD	Protein N-linked glycosylation →	+0.060	+0.145	<.001	<.001	3	14
STAD	Morphogenesis of a branching structure →	+0.064	+0.184	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,477 associations by consensus.

Regulation of intracellular protein transport by CYP46A4P expression — STAD

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