CYP2U1

Across TCGA patient cohorts, CYP2U1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,434 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP2U1-associated genes across cancer lineages are CDCA8, NCF4, and SLCO2B1. Each is linked with CYP2U1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP2U1-to-partner and partner-to-CYP2U1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP2U1 versus CDCA8 in UCEC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2U1→partner) and Y-score (partner→CYP2U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA8 →	-1.152	-0.355	.005	.007	3	4
PDAC	NCF4 →	+0.513	+0.387	.001	.002	3	3
CCRCC	SLCO2B1 →	+0.521	+0.277	.009	.005	3	3
PDAC	DPEP2 →	+0.627	+0.386	<.001	.004	3	3
OV	PSTPIP1 →	+0.681	+0.383	.002	.002	3	3
PDAC	FLAD1 →	-0.370	-0.441	.004	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,434 associations by consensus.

CYP2U1 vs CDCA8 — UCEC

Explore this scatter interactively →