CYP2G1P

Across TCGA patient cohorts, CYP2G1P mutation is significantly associated with the RNA expression of many other genes, with 1,142 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP2G1P-associated genes across cancer lineages are MIR98, RNU6-6P, and MIR7702. Each is linked with CYP2G1P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2G1P-to-partner and partner-to-CYP2G1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR98 grouped by CYP2G1P-low versus CYP2G1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2G1P→partner) and Y-score (partner→CYP2G1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR98 →	+0.333	+2.664	<.001	.002	3	1
UCEC	RNU6-6P →	+0.535	+2.077	<.001	.005	3	1
UCEC	MIR7702 →	+0.229	+4.253	<.001	.004	3	1
UCEC	RPS29P32 →	+0.516	+2.462	<.001	.004	3	1
UCEC	PIGW →	+0.655	+3.917	.002	<.001	3	1
UCEC	GTSE1-DT →	+0.437	+3.249	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,142 associations by consensus.

MIR98 by CYP2G1P expression — UCEC

Explore this box plot interactively →