Across TCGA patient cohorts, CYP2A7P1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP2A7P1-associated genes across cancer lineages are MIR7845, IMMP1LP2, and MIR3181. Each is linked with CYP2A7P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2A7P1-to-partner and partner-to-CYP2A7P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A7P1→partner) and Y-score (partner→CYP2A7P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR7845 →	+0.349	+4.034	<.001	.004	3	2
COAD	IMMP1LP2 →	+0.222	+4.081	.001	.004	3	1
COAD	MIR3181 →	+1.111	+3.754	<.001	.008	3	1
COAD	SNRPCP20 →	+0.300	+3.831	.006	.007	3	1
BLCA	FGF7P1 →	+0.189	+7.640	<.001	.009	3	1
LGG	ELOA3DP →	+0.024	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

CYP2A7P1 survival (RNA) · tumor vs normal (RNA) · all CYP2A7P1 data types