Across TCGA patient cohorts, CYP2A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,087 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYP2A7-associated GO terms across cancer lineages are Protein stabilization, Obsolete histone modification, and Hematopoietic progenitor cell differentiation. Each is linked with CYP2A7 in more than 20 cancer types. Because this analysis shows association rather than direction, both CYP2A7-to-partner and partner-to-CYP2A7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A7→partner) and Y-score (partner→CYP2A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.058	+0.155	<.001	<.001	3	21
ESCA	Obsolete histone modification →	+0.087	+0.221	<.001	<.001	3	21
STAD	Hematopoietic progenitor cell differentiation →	+0.052	+0.122	<.001	<.001	3	21
THYM	Golgi vesicle transport →	+0.064	+0.057	<.001	<.001	3	21
THYM	Obsolete regulation of histone H3-K4 methylation →	+0.093	+0.063	<.001	<.001	3	20
ESCA	Protein acetylation →	+0.055	+0.181	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,087 associations by consensus.

Exploration

CYP2A7 survival (RNA) · tumor vs normal (RNA) · all CYP2A7 data types