Across TCGA cell cohorts, CYP2A7 RNA expression is significantly associated with the RNA expression of many other genes, with 3,697 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CYP2A7-associated genes across cancer lineages are CYP2A6, ZBED6, and PGLYRP1. Each is linked with CYP2A7 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYP2A7-to-partner and partner-to-CYP2A7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A7→partner) and Y-score (partner→CYP2A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CYP2A6 →	+1.212	+0.613	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	ZBED6 →	+0.965	+0.076	<.001	.002	3	5
STOMACH	PGLYRP1 →	+0.255	+0.088	.002	.002	2	6
LUNG_NSCLC_LUSC	KCTD13 →	+1.360	+0.047	.002	.008	3	4
UPPER_AERODIGESTIVE_TRACT	LENG8 →	+1.649	+0.108	<.001	.002	3	4
BREAST	CSAD →	+1.331	+0.308	<.001	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,697 associations by consensus.

Exploration

CYP2A7 survival (RNA) · tumor vs normal (RNA) · all CYP2A7 data types