Across TCGA cell cohorts, CYP2A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,105 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CYP2A7-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Cilium or flagellum-dependent cell motility, and Protein destabilization. Each is linked with CYP2A7 in more than 6 cancer types. Because this analysis shows association rather than direction, both CYP2A7-to-partner and partner-to-CYP2A7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A7→partner) and Y-score (partner→CYP2A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.107	-0.078	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.104	-0.078	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.086	+0.100	<.001	.004	3	6
BLOOD_Lymphoma	Cellular response to nutrient levels →	+0.027	+0.035	.007	.004	3	6
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.104	-0.078	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of cilium assembly →	+0.043	+0.109	.008	.009	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

Exploration

CYP2A7 survival (RNA) · tumor vs normal (RNA) · all CYP2A7 data types