CYP27A1

Across TCGA patient cohorts, CYP27A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,326 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP27A1-associated proteins across cancer lineages are NAA35, WAS, and WDFY4. Each is linked with CYP27A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP27A1-to-partner and partner-to-CYP27A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP27A1 versus NAA35 in COAD, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP27A1→partner) and Y-score (partner→CYP27A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NAA35 →	-0.250	-0.891	.001	<.001	3	6
GBM	WAS →	+0.593	+0.579	<.001	.002	3	6
LSCC	WDFY4 →	+0.522	+1.104	<.001	<.001	3	6
LUAD	CAPG →	+0.418	+0.872	<.001	<.001	3	6
GBM	DAB2 →	+0.650	+0.523	<.001	.001	3	6
HNSC	FBP1 →	+0.941	+1.102	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,326 associations by consensus.

CYP27A1 vs NAA35 — COAD

Explore this scatter interactively →