CYP26A1

Across TCGA patient cohorts, CYP26A1 protein abundance is significantly associated with the RNA expression of many other genes, with 634 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP26A1-associated genes across cancer lineages are CDC37L1, PLA2G4A, and SMPDL3B. Each is linked with CYP26A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP26A1-to-partner and partner-to-CYP26A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP26A1 versus CDC37L1 in UCEC, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP26A1→partner) and Y-score (partner→CYP26A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDC37L1 →	-0.519	-0.977	.001	.007	3	1
UCEC	PLA2G4A →	-2.564	-1.060	.004	.002	3	1
UCEC	SMPDL3B →	-0.895	-1.094	<.001	.001	3	1
UCEC	MORC4 →	-1.407	-0.988	<.001	.007	3	1
UCEC	NTPCR →	-1.004	-1.147	.006	.006	3	1
UCEC	REV1 →	-0.627	-1.003	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

CYP26A1 vs CDC37L1 — UCEC

Explore this scatter interactively →