CYCSP39

Across TCGA patient cohorts, CYCSP39 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,323 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP39-associated GO terms across cancer lineages are Mitochondrial translational elongation, Regulation of chromosome condensation, and Positive regulation of chromosome condensation. Each is linked with CYCSP39 in more than 12 cancer types. Because this analysis shows association rather than direction, both CYCSP39-to-partner and partner-to-CYCSP39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translational elongation grouped by CYCSP39-low versus CYCSP39-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP39→partner) and Y-score (partner→CYCSP39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Mitochondrial translational elongation →	+0.050	+0.176	<.001	<.001	3	13
STAD	Regulation of chromosome condensation →	+0.053	+0.174	<.001	<.001	3	11
TGCT	Positive regulation of chromosome condensation →	+0.059	+0.107	<.001	.003	3	10
ACC	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.040	+0.156	<.001	<.001	3	10
STAD	Protein-DNA covalent cross-linking repair →	+0.033	+0.165	<.001	<.001	3	10
STAD	Negative regulation of chromosome organization →	+0.044	+0.154	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,323 associations by consensus.

Mitochondrial translational elongation by CYCSP39 expression — ACC

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