CYCSP33

Across TCGA patient cohorts, CYCSP33 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,540 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP33-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Protein localization to plasma membrane, and Regulation of RNA splicing. Each is linked with CYCSP33 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYCSP33-to-partner and partner-to-CYCSP33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by CYCSP33-low versus CYCSP33-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP33→partner) and Y-score (partner→CYCSP33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alternative mRNA splicing, via spliceosome →	+0.077	+0.091	<.001	<.001	3	9
STAD	Protein localization to plasma membrane →	+0.064	+0.088	<.001	<.001	3	9
STAD	Regulation of RNA splicing →	+0.077	+0.095	<.001	<.001	3	9
STAD	Vesicle budding from membrane →	+0.068	+0.085	<.001	<.001	3	9
STAD	Lytic vacuole organization →	+0.062	+0.088	<.001	<.001	3	8
STAD	Obsolete ubiquitin-dependent ERAD pathway →	+0.065	+0.090	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,540 associations by consensus.

Alternative mRNA splicing, via spliceosome by CYCSP33 expression — STAD

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