CYCSP33

Across TCGA pan-cancer cohorts, CYCSP33 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CYCSP33’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where CYCSP33 RNA is repressed in tumor relative to normal tissue. In most cancer types CYCSP33 is over-expressed in tumor, although a few such as PAAD and COAD show the opposite, repressed pattern.

PAAD and COAD are the cancer types where CYCSP33 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYCSP33 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Female	All	−0.285	.048	2	view →
COAD	Male	II,III,IV	−0.067	.044	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

CYCSP33–PAAD

Open the PAAD breakdown →