CYCSP33

Across TCGA pan-cancer cohorts, CYCSP33 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CYCSP33 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CYCSP33 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYCSP33 expression acts as an unfavorable survival marker, although some lineages such as LAML and ESCA show a favorable association.

OV, BLCA, and HNSC are the cancer types where CYCSP33 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	All	0.350	0.550	<.001	126	view →
BLCA	OS	Tertile	All	0.183	0.692	<.001	72	view →
HNSC	DFS	Tertile	II,III,IV	0.193	0.566	.004	60	view →
UCEC	OS	Tertile	IV	0.302	0.766	.001	60	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	45	view →
KIRP	OS	Tertile	II,III,IV	0.176	0.743	.007	36	view →
LAML	DFS	Median	All	0.565	0.225	<.001	34	view →
READ	DFS	Tertile	IV	0.158	0.668	.001	27	view →
SKCM	DFS	Tertile	All	0.393	0.772	.002	12	view →
PCPG	OS	Tertile	All	0.273	0.970	.005	12	view →
THCA	DFS	Tertile	All	0.520	0.824	.017	9	view →
CHOL	OS	Tertile	All	0.154	0.793	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CYCSP33–OV (DFS)

Open the OV breakdown →