CYBA

Across TCGA cell cohorts, CYBA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,148 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYBA-associated GO terms across cancer lineages are Response to L-glutamine, Cellular response to L-glutamine, and Regulation of renal output by angiotensin. Each is linked with CYBA in more than 15 cancer types. Because this analysis shows association rather than direction, both CYBA-to-partner and partner-to-CYBA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to L-glutamine grouped by CYBA-low versus CYBA-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYBA→partner) and Y-score (partner→CYBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to L-glutamine →	+2.054	+5.679	<.001	<.001	3	16
SOFT_TISSUE	Cellular response to L-glutamine →	+2.054	+5.679	<.001	<.001	3	16
SOFT_TISSUE	Regulation of renal output by angiotensin →	+2.101	+6.043	<.001	<.001	3	16
SOFT_TISSUE	Regulation of blood volume by renin-angiotensin →	+2.162	+5.608	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of defense response to bacterium →	+0.494	+3.465	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Negative regulation of glomerular filtration →	+1.232	+4.839	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,148 associations by consensus.

Response to L-glutamine by CYBA expression — SOFT_TISSUE

Explore this box plot interactively →