CYB5R1

Across TCGA patient cohorts, CYB5R1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,646 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYB5R1-associated genes across cancer lineages are AURKB, CDCA3, and LMNB1. Each is linked with CYB5R1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYB5R1-to-partner and partner-to-CYB5R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5R1 versus AURKB in OV, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R1→partner) and Y-score (partner→CYB5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AURKB →	-1.039	-0.449	<.001	<.001	3	9
BRCA	CDCA3 →	-1.077	-0.470	<.001	.001	3	8
OV	LMNB1 →	-0.949	-0.368	<.001	.001	3	8
LSCC	ECT2 →	-0.879	-0.433	<.001	<.001	3	8
BRCA	CENPA →	-1.145	-0.411	<.001	<.001	3	8
HNSC	HELLS →	-0.801	-0.477	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,646 associations by consensus.

CYB5R1 vs AURKB — OV

Explore this scatter interactively →