CYB561D1

Across TCGA patient cohorts, CYB561D1 mutation is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB561D1-associated genes across cancer lineages are UPP2-IT1, GPATCH11, and SLC25A28. Each is linked with CYB561D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB561D1-to-partner and partner-to-CYB561D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UPP2-IT1 grouped by CYB561D1-low versus CYB561D1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561D1→partner) and Y-score (partner→CYB561D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	UPP2-IT1 →	+0.168	+4.410	<.001	.006	3	1
UCEC	GPATCH11 →	+0.496	+3.595	.006	.001	3	1
UCEC	SLC25A28 →	+0.414	+3.353	.002	.005	3	1
UCEC	WHAMM →	+0.683	+3.386	<.001	.004	3	1
UCEC	NTAN1 →	+0.557	+3.201	.001	.009	3	1
UCEC	SLC30A2 →	-1.150	-3.459	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

UPP2-IT1 by CYB561D1 expression — SKCM

Explore this box plot interactively →