CYB561D1

Across TCGA patient cohorts, CYB561D1 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB561D1-associated genes across cancer lineages are FOXO3a, S6_pS240_S244, and Shc_pY317. Each is linked with CYB561D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB561D1-to-partner and partner-to-CYB561D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a grouped by CYB561D1-low versus CYB561D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561D1→partner) and Y-score (partner→CYB561D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.120	-3.156	.031	.020	3	1
UCEC	S6_pS240_S244 →	+0.444	+3.169	.046	.020	3	1
UCEC	Shc_pY317 →	-0.220	-3.000	.008	.036	3	1
UCEC	c-Jun_pS73 →	-0.176	-2.990	.044	.036	2	1
UCEC	AR →	-0.421	-3.169	.040	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FOXO3a by CYB561D1 expression — UCEC

Explore this box plot interactively →