CYB561A3

Across TCGA patient cohorts, CYB561A3 mutation is significantly associated with the RNA expression of many other genes, with 2,457 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB561A3-associated genes across cancer lineages are MIR552, LINC01399, and MIR548AL. Each is linked with CYB561A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB561A3-to-partner and partner-to-CYB561A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR552 grouped by CYB561A3-low versus CYB561A3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561A3→partner) and Y-score (partner→CYB561A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR552 →	+1.496	+8.055	<.001	.007	3	2
UCEC	LINC01399 →	+0.188	+1.793	<.001	.004	3	2
SKCM	MIR548AL →	+0.224	+5.219	<.001	.002	3	2
BLCA	LINC00458 →	+1.312	+4.926	<.001	.002	3	2
BLCA	YWHAEP4 →	+0.226	+6.040	<.001	.001	3	2
COAD	MIR615 →	+1.019	+5.693	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,457 associations by consensus.

MIR552 by CYB561A3 expression — BRCA

Explore this box plot interactively →