CXorf58

Across TCGA cell cohorts, CXorf58 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,373 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CXorf58-associated GO terms across cancer lineages are Regulation of hormone secretion, Mesonephric tubule morphogenesis, and Maintenance of protein location in nucleus. Each is linked with CXorf58 in more than 4 cancer types. Because this analysis shows association rather than direction, both CXorf58-to-partner and partner-to-CXorf58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hormone secretion grouped by CXorf58-low versus CXorf58-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf58→partner) and Y-score (partner→CXorf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of hormone secretion →	-0.041	-0.108	<.001	<.001	3	5
BREAST	Mesonephric tubule morphogenesis →	-0.113	-0.083	<.001	.004	3	5
PANCREAS	Maintenance of protein location in nucleus →	+0.067	+0.074	.006	.007	3	5
LARGE_INTESTINE	Protein localization to microtubule organizing center →	+0.056	+0.066	<.001	.005	3	5
OVARY	Regulation of DNA damage checkpoint →	+0.070	+0.046	<.001	.009	3	5
LARGE_INTESTINE	Protein localization to centrosome →	+0.056	+0.066	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,373 associations by consensus.

Regulation of hormone secretion by CXorf58 expression — BREAST

Explore this box plot interactively →