CXorf21

Across TCGA patient cohorts, CXorf21 protein abundance is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXorf21-associated genes across cancer lineages are TMEM97, ZHX1-C8orf76, and F11R. Each is linked with CXorf21 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXorf21-to-partner and partner-to-CXorf21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXorf21 versus TMEM97 in LSCC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf21→partner) and Y-score (partner→CXorf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM97 →	-1.595	-0.675	<.001	<.001	3	2
LSCC	ZHX1-C8orf76 →	-0.386	-0.477	.001	.002	3	2
LSCC	F11R →	-0.648	-0.517	.008	<.001	3	2
LSCC	TLCD5 →	-0.542	-0.338	.008	.007	3	2
HNSC	KCNK15 →	+0.766	+0.259	.005	.001	3	1
HNSC	PDCD4 →	+1.660	+0.259	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

CXorf21 vs TMEM97 — LSCC

Explore this scatter interactively →