CXCR2

Across TCGA patient cohorts, CXCR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,816 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCR2-associated proteins across cancer lineages are MMP8, MMP9, and MPO. Each is linked with CXCR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXCR2-to-partner and partner-to-CXCR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCR2 versus MMP8 in GBM, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCR2→partner) and Y-score (partner→CXCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP8 →	+1.376	+0.983	<.001	<.001	3	10
UCEC	MMP9 →	+1.226	+1.072	<.001	<.001	3	10
GBM	MPO →	+1.036	+0.923	<.001	<.001	3	10
GBM	ARG1 →	+1.036	+1.056	<.001	<.001	3	10
PDAC	YTHDC1_S308 →	-1.581	-0.985	<.001	<.001	3	10
GBM	PRTN3 →	+1.385	+0.958	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,816 associations by consensus.

CXCR2 vs MMP8 — GBM

Explore this scatter interactively →