CXCL13

Across TCGA patient cohorts, CXCL13 protein abundance is significantly associated with the RNA expression of many other genes, with 8,173 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL13-associated genes across cancer lineages are CD38, IL2RB, and SLA2. Each is linked with CXCL13 in more than 5 cancer types. Because this analysis shows association rather than direction, both CXCL13-to-partner and partner-to-CXCL13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL13 versus CD38 in OV, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL13→partner) and Y-score (partner→CXCL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD38 →	+2.147	+2.279	.002	.002	3	6
PDAC	IL2RB →	+0.878	+1.120	.002	<.001	3	5
LSCC	SLA2 →	+0.899	+1.165	<.001	<.001	3	5
PDAC	MAP4K1 →	+0.901	+0.967	.001	.002	3	5
LSCC	CD37 →	+0.878	+1.042	<.001	<.001	3	5
OV	CD79A →	+3.174	+1.367	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,173 associations by consensus.

CXCL13 vs CD38 — OV

Explore this scatter interactively →