CXADR

Across TCGA pan-cancer cohorts, CXADR mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CXADR data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CXADR mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CXADR expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where CXADR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.013	72	view →
PDAC	OS	Quartile	All	0.633	0.324	.010	17	view →
LUAD	DFS	Median	II,III,IV	0.739	0.968	.001	15	view →
HNSC	DFS	Median	II,III,IV	0.770	0.553	.013	11	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.759	.012	9	view →
GBM	DFS	Tertile	All	0.939	0.646	.008	3	view →
CCRCC	DFS	Median	II,III,IV	0.391	0.762	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CXADR–COAD (DFS)

Open the COAD breakdown →