CXADR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CXADR protein abundance is significantly associated with the RNA expression of many other genes, with 13,061 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXADR-associated genes across cancer lineages are RPL39P40, FAM78A, and BTG3-AS1. Each is linked with CXADR in more than 8 cancer types. Because this analysis shows association rather than direction, both CXADR-to-partner and partner-to-CXADR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXADR versus RPL39P40 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXADR→partner) and Y-score (partner→CXADR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRPL39P40 →+1.410+0.544.002.00939
HNSCFAM78A →-0.674-0.485<.001.00337
HNSCBTG3-AS1 →+0.531+0.818.002<.00137
UCECWAS →-0.647-0.747.002.00137
LSCCBTF3L4P1 →+1.121+0.923<.001<.00137
OVIFFO1 →-0.962-0.610<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,061 associations by consensus.

CXADR vs RPL39P40 — OV

Per-sample scatter of CXADR vs RPL39P40 in OV (Pearson r = 0.41).

Explore this scatter interactively →

Exploration