CXADR

Across TCGA cell cohorts, CXADR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,616 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CXADR-associated GO terms across cancer lineages are Regulation of AV node cell action potential, Cardiac muscle cell-cardiac muscle cell adhesion, and Germ cell migration. Each is linked with CXADR in more than 18 cancer types. Because this analysis shows association rather than direction, both CXADR-to-partner and partner-to-CXADR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of AV node cell action potential grouped by CXADR-low versus CXADR-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXADR→partner) and Y-score (partner→CXADR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of AV node cell action potential →	+1.628	+2.046	<.001	<.001	3	19
CNS	Cardiac muscle cell-cardiac muscle cell adhesion →	+0.913	+1.338	<.001	<.001	3	11
PANCREAS	Germ cell migration →	+1.033	+1.440	<.001	.005	2	11
SOFT_TISSUE	Keratinocyte development →	-0.445	-1.295	.004	.005	3	9
BONE	Positive regulation of calcium ion import across plasma membrane →	-0.139	-1.810	.006	.001	3	9
BLOOD_Leukemia	Copper ion export →	-0.160	-0.575	.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,616 associations by consensus.

Regulation of AV node cell action potential by CXADR expression — OESOPHAGUS

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