CTU1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTU1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,338 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTU1-associated genes across cancer lineages are BCL2A1, FMO5, and GFRA1. Each is linked with CTU1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTU1-to-partner and partner-to-CTU1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTU1 versus BCL2A1 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTU1→partner) and Y-score (partner→CTU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCABCL2A1 →+1.003+0.255.005.00133
BRCAFMO5 →-1.172-0.367.001<.00133
BRCAGFRA1 →-1.725-0.184<.001.00133
PDACCACNA2D3 →-0.571-0.392<.001<.00133
BRCAHDAC11 →-0.584-0.270.004.00133
BRCANUDT13 →-0.318-0.250.007<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,338 associations by consensus.

CTU1 vs BCL2A1 — BRCA

Per-sample scatter of CTU1 vs BCL2A1 in BRCA (Pearson r = 0.42).

Explore this scatter interactively →

Exploration