CTU1

Across TCGA pan-cancer cohorts, CTU1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CTU1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CTU1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CTU1 is over-expressed in tumor.

KIRC, COAD, and BLCA are the cancer types where CTU1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CTU1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.552	<.001	12	view →
COAD	Female	All	+1.560	<.001	11	view →
BLCA	Male	All	+0.850	<.001	11	view →
HNSC	Male	All	+0.906	<.001	10	view →
STAD	All	II,III,IV	+1.027	<.001	9	view →
LIHC	Female	All	+0.941	<.001	9	view →
LUSC	Male	II,III,IV	+1.008	<.001	8	view →
BRCA	All	All	+0.230	.003	6	view →
CHOL	Male	All	+1.551	<.001	5	view →
KIRP	All	II,III,IV	+0.503	.002	5	view →
READ	All	All	+1.420	.004	3	view →
PRAD	All	All	+0.362	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CTU1–KIRC

Open the KIRC breakdown →