CTRL

Across TCGA patient cohorts, CTRL protein abundance is significantly associated with the RNA expression of many other genes, with 1,352 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CTRL-associated genes across cancer lineages are SLC25A1, TRIOBP, and RTCB. Each is linked with CTRL in more than 1 cancer types. Because this analysis shows association rather than direction, both CTRL-to-partner and partner-to-CTRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTRL versus SLC25A1 in PDAC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTRL→partner) and Y-score (partner→CTRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC25A1 →	-0.319	-0.673	<.001	<.001	3	1
PDAC	TRIOBP →	-0.278	-0.430	<.001	.001	3	1
PDAC	RTCB →	-0.168	-0.385	.007	.004	3	1
PDAC	TSPO →	-0.479	-0.568	<.001	.003	3	1
PDAC	TTLL12 →	-0.426	-0.567	.001	.002	3	1
PDAC	L3MBTL2 →	-0.190	-0.421	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,352 associations by consensus.

CTRL vs SLC25A1 — PDAC

Explore this scatter interactively →