CTC1

Across TCGA patient cohorts, CTC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,358 significant associations in total. OV shows the largest number of these associations.

The most reproducible CTC1-associated genes across cancer lineages are GPR35, HAS2, and SOWAHC. Each is linked with CTC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTC1-to-partner and partner-to-CTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTC1 versus GPR35 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTC1→partner) and Y-score (partner→CTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GPR35 →	+0.750	+0.311	<.001	.002	3	2
PDAC	HAS2 →	+1.077	+0.910	.003	.003	3	2
LUAD	SOWAHC →	+0.422	+0.246	.003	<.001	3	2
OV	GLI2 →	+0.997	+0.619	<.001	.007	3	2
OV	RPS10P5 →	-1.003	-0.613	.007	.004	3	2
HNSC	USP54 →	-0.644	-0.342	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,358 associations by consensus.

CTC1 vs GPR35 — LUAD

Explore this scatter interactively →