CTAGE8

Across TCGA patient cohorts, CTAGE8 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTAGE8-associated genes across cancer lineages are RNU6-434P, MORC1-AS1, and RNU6-889P. Each is linked with CTAGE8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTAGE8-to-partner and partner-to-CTAGE8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-434P grouped by CTAGE8-low versus CTAGE8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAGE8→partner) and Y-score (partner→CTAGE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-434P →	+0.438	+5.513	<.001	.004	3	2
COAD	MORC1-AS1 →	+0.142	+7.741	.001	.009	3	2
COAD	RNU6-889P →	+0.569	+7.741	<.001	.009	3	2
UCEC	SFPQP1 →	+0.076	+3.741	<.001	.003	3	2
UCEC	MIR378E →	+0.608	+4.453	<.001	.006	3	1
UCEC	MIR4648 →	+1.587	+4.106	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

RNU6-434P by CTAGE8 expression — SKCM

Explore this box plot interactively →