CTAGE8

Across TCGA pan-cancer cohorts, CTAGE8 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CTAGE8 data layer compared with 1 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher CTAGE8 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CTAGE8 expression acts as an unfavorable survival marker, although some lineages such as MESO and SARC show a favorable association.

MESO, LAML, and CHOL are the cancer types where CTAGE8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	IV	0.609	0.222	.003	85	view →
LAML	DFS	Quartile	All	0.367	0.627	<.001	34	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	27	view →
LGG	OS	Tertile	All	0.766	0.905	.003	18	view →
SARC	OS	Quartile	All	0.915	0.784	.008	16	view →
UCEC	DFS	Median	All	0.559	0.703	.007	16	view →
DLBC	OS	Median	II,III,IV	1.000	0.391	.006	11	view →
ESCA	OS	Median	III,IV	0.532	0.307	.016	10	view →
GBM	DFS	Tertile	All	0.116	0.319	.005	9	view →
BRCA	DFS	Tertile	IV	0.289	0.804	.017	8	view →
KIRC	OS	Quartile	All	0.744	0.837	.021	8	view →
KIRP	DFS	Median	III,IV	0.810	0.590	.019	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CTAGE8–MESO (DFS)

Open the MESO breakdown →