CT45A10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CT45A10 protein abundance is significantly associated with the RNA expression of many other genes, with 603 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CT45A10-associated genes across cancer lineages are CYP2D6, GSS, and MAPK3. Each is linked with CT45A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT45A10-to-partner and partner-to-CT45A10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CT45A10 versus CYP2D6 in LSCC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT45A10→partner) and Y-score (partner→CT45A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCYP2D6 →+0.904+1.754<.001.00831
LSCCGSS →+0.466+1.540.007<.00131
LSCCMAPK3 →+0.780+1.530<.001.00131
LSCCGDPD3 →+0.760+1.508.006<.00131
LSCCDHODH →+0.410+1.266.002.00931
LSCCAXIN1 →+0.521+1.585.002<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 603 associations by consensus.

CT45A10 vs CYP2D6 — LSCC

Per-sample scatter of CT45A10 vs CYP2D6 in LSCC (Pearson r = 0.63).

Explore this scatter interactively →

Exploration