CSTF2T

Across TCGA patient cohorts, CSTF2T mutation is significantly associated with the RNA expression of many other genes, with 3,999 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSTF2T-associated genes across cancer lineages are TSPY18P, RNU6-4P, and CEND1P1. Each is linked with CSTF2T in more than 2 cancer types. Because this analysis shows association rather than direction, both CSTF2T-to-partner and partner-to-CSTF2T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY18P grouped by CSTF2T-low versus CSTF2T-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2T→partner) and Y-score (partner→CSTF2T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPY18P →	+0.072	+7.473	<.001	.007	3	3
UCEC	RNU6-4P →	+0.368	+1.649	.001	.001	3	3
STAD	CEND1P1 →	+0.139	+4.782	.001	.003	3	2
LIHC	NUS1P4 →	+0.066	+5.758	<.001	.003	3	2
LIHC	TNR-IT1 →	+0.078	+6.902	<.001	<.001	3	2
BRCA	RNA5SP109 →	+0.477	+5.505	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,999 associations by consensus.

TSPY18P by CSTF2T expression — BRCA

Explore this box plot interactively →