Q-omics provides the consensus-scored TNR-IT1 profile across patient tissues and cancer cell-line models. TNR-IT1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, TNR-IT1 RNA expression shows 8,968 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight ESCA, and GBM as cancer lineages where TNR-IT1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TNR-IT1 survival associations across molecular data types. TNR-IT1 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TNR-IT1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	ESCA (36)	view →

This table ranks reproducible TNR-IT1 RNA expression–survival associations across cancer types. High TNR-IT1 expression shows unfavorable associations in ESCA, UCEC, TGCT, SKCM and KIRC, but favorable associations in PAAD. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for TNR-IT1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
PAAD	OS	Tertile	II,III,IV	1.000	0.326	.023	24	view →
UCEC	DFS	Tertile	All	0.722	0.847	.014	24	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
KIRC	DFS	Tertile	IV	0.293	0.653	.016	18	view →

Pink = unfavorable, green = favorable. all 12 lineages →

TNR-IT1-ESCA (OS)

Kaplan–Meier survival curve for TNR-IT1 RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TNR-IT1 in patient tissues and cancer cell lines. In patient samples, TNR-IT1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	8,968	GBM (7389)	view →
RNA	6,986	COAD (2481)	view →