CST9L

Across TCGA cell cohorts, CST9L mutation is significantly associated with the mutation status of many other genes, with 654 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CST9L-associated genes across cancer lineages are PRICKLE3, SLC32A1, and STAMBP. Each is linked with CST9L in more than 1 cancer types. Because this analysis shows association rather than direction, both CST9L-to-partner and partner-to-CST9L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRICKLE3 grouped by CST9L-low versus CST9L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST9L→partner) and Y-score (partner→CST9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRICKLE3 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	SLC32A1 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	STAMBP →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	CAPN9 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	NIBAN1 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	CLPB →	+4.736	+5.560	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 654 associations by consensus.

PRICKLE3 by CST9L expression — BLOOD_Leukemia

Explore this box plot interactively →