CSRP1

Across TCGA patient cohorts, CSRP1 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSRP1-associated genes across cancer lineages are SFPQP1, RNU6-1228P, and MIR4727. Each is linked with CSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSRP1-to-partner and partner-to-CSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFPQP1 grouped by CSRP1-low versus CSRP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRP1→partner) and Y-score (partner→CSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SFPQP1 →	+0.070	+3.681	<.001	.003	3	2
LUSC	RNU6-1228P →	+0.480	+6.191	<.001	.001	3	2
UCEC	MIR4727 →	+0.449	+3.329	<.001	.005	3	1
COAD	SNORD113-4 →	+0.969	+3.541	<.001	.007	3	1
COAD	MIR33B →	+1.100	+3.879	<.001	.004	3	1
COAD	IGHD2-15 →	+2.380	+3.791	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

SFPQP1 by CSRP1 expression — COAD

Explore this box plot interactively →