CSPG5

Across TCGA patient cohorts, CSPG5 mutation is significantly associated with the RNA expression of many other genes, with 1,111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSPG5-associated genes across cancer lineages are MED28P8, NDE1P2, and TUBGCP5. Each is linked with CSPG5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSPG5-to-partner and partner-to-CSPG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MED28P8 grouped by CSPG5-low versus CSPG5-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSPG5→partner) and Y-score (partner→CSPG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MED28P8 →	+0.246	+5.039	<.001	.008	3	2
READ	NDE1P2 →	+0.049	+5.219	<.001	.006	3	2
UCEC	TUBGCP5 →	+0.484	+2.534	<.001	.001	3	2
COAD	PACRG-AS2 →	+0.069	+4.136	<.001	.008	3	2
COAD	PIGPP3 →	+0.135	+3.280	.001	.008	3	2
SKCM	OR6C75 →	+0.096	+5.970	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,111 associations by consensus.

MED28P8 by CSPG5 expression — READ

Explore this box plot interactively →