CSP1

Across TCGA pan-cancer cohorts, CSP1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CSP1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CSP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSP1 expression acts as an unfavorable survival marker, although some lineages such as UCS and COAD show a favorable association.

UVM, MESO, and KICH are the cancer types where CSP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.032	0.762	<.001	90	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	36	view →
KICH	OS	Tertile	All	0.248	0.881	.015	21	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
LGG	OS	Tertile	All	0.785	0.903	.001	18	view →
PCPG	DFS	Tertile	All	0.214	0.808	.002	12	view →
KIRC	OS	Tertile	All	0.785	0.891	.015	12	view →
COAD	OS	Tertile	All	0.956	0.848	.025	9	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	9	view →
THCA	OS	Tertile	IV	0.252	1.000	<.001	9	view →
TGCT	DFS	Median	All	0.909	0.756	.008	8	view →
READ	DFS	Tertile	All	0.943	0.785	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CSP1–UVM (DFS)

Open the UVM breakdown →