CSP1

Across TCGA pan-cancer cohorts, CSP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CSP1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CSP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CSP1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA, UCEC, and COAD are the cancer types where CSP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	IV	−0.385	.001	4	view →
UCEC	All	All	+0.043	.046	2	view →
COAD	All	All	+0.060	.044	1	view →
LUSC	All	II,III,IV	+0.026	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CSP1–BRCA

Open the BRCA breakdown →