CSN1S2AP

Across TCGA patient cohorts, CSN1S2AP mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSN1S2AP-associated genes across cancer lineages are RPL32P21, MIR3129, and RN7SL230P. Each is linked with CSN1S2AP in more than 1 cancer types. Because this analysis shows association rather than direction, both CSN1S2AP-to-partner and partner-to-CSN1S2AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P21 grouped by CSN1S2AP-low versus CSN1S2AP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN1S2AP→partner) and Y-score (partner→CSN1S2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL32P21 →	+0.320	+3.652	.008	.008	3	1
UCEC	MIR3129 →	+0.515	+3.430	.003	.007	3	1
UCEC	RN7SL230P →	+0.443	+3.233	.001	.005	3	1
UCEC	RN7SL140P →	+0.136	+4.260	.006	.007	3	1
UCEC	RNU6-698P →	+0.201	+4.923	<.001	.002	3	1
UCEC	RNU6-353P →	+1.001	+3.834	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

RPL32P21 by CSN1S2AP expression — UCEC

Explore this box plot interactively →