CSMD3

Across TCGA cell cohorts, CSMD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,893 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CSMD3-associated GO terms across cancer lineages are Neuroblast differentiation, Regulation of phosphatidylcholine metabolic process, and tRNA transcription by RNA polymerase III. Each is linked with CSMD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CSMD3-to-partner and partner-to-CSMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuroblast differentiation grouped by CSMD3-low versus CSMD3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD3→partner) and Y-score (partner→CSMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Neuroblast differentiation →	+1.286	+1.255	.003	<.001	3	5
BLOOD_Leukemia	Regulation of phosphatidylcholine metabolic process →	+0.143	+0.510	<.001	.001	3	5
BONE	tRNA transcription by RNA polymerase III →	+0.109	+0.895	.005	.008	3	5
BLOOD_Lymphoma	Negative regulation of phospholipase C/protein kinase C signal transduction →	-0.314	-0.072	.001	.002	3	4
BONE	Protein transport within lipid bilayer →	-1.022	-1.297	.001	<.001	3	4
BONE	Acetylcholine catabolic process →	+1.218	+1.092	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

Neuroblast differentiation by CSMD3 expression — BONE

Explore this box plot interactively →