CRYM

Across TCGA patient cohorts, CRYM RNA expression is significantly associated with the protein abundance of many other proteins, with 20,146 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYM-associated proteins across cancer lineages are PLEKHA7_S903, DLG3, and FNDC3B. Each is linked with CRYM in more than 4 cancer types. Because this analysis shows association rather than direction, both CRYM-to-partner and partner-to-CRYM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYM versus PLEKHA7_S903 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYM→partner) and Y-score (partner→CRYM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA7_S903 →	+0.832	+0.842	<.001	<.001	3	5
GBM	DLG3 →	+0.641	+1.731	<.001	<.001	3	5
GBM	FNDC3B →	-0.445	-1.245	<.001	<.001	3	5
GBM	MMP14 →	-0.478	-0.922	<.001	<.001	3	5
GBM	SH3BGRL2 →	+0.534	+1.324	<.001	<.001	3	5
COAD	RBM47 →	+0.263	+0.674	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,146 associations by consensus.

CRYM vs PLEKHA7_S903 — LSCC

Explore this scatter interactively →