CRYM

Across TCGA patient cohorts, CRYM protein abundance is significantly associated with the RNA expression of many other genes, with 11,161 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CRYM-associated genes across cancer lineages are NR3C2, VSIG2, and GNA14. Each is linked with CRYM in more than 4 cancer types. Because this analysis shows association rather than direction, both CRYM-to-partner and partner-to-CRYM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYM versus NR3C2 in LUAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYM→partner) and Y-score (partner→CRYM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NR3C2 →	+0.871	+0.846	<.001	<.001	3	5
COAD	VSIG2 →	+1.965	+0.402	.002	.002	3	5
BRCA	GNA14 →	+1.252	+0.966	<.001	.004	3	5
GBM	ENPP5 →	+1.302	+0.521	.002	.005	2	5
OV	MLPH →	+1.560	+0.921	<.001	.001	3	4
LUAD	LDHD →	+1.150	+1.313	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,161 associations by consensus.

CRYM vs NR3C2 — LUAD

Explore this scatter interactively →