CRYM

Across TCGA cell cohorts, CRYM mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CRYM-associated genes across cancer lineages are OR13C9 and TAAR8. Each is linked with CRYM in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYM-to-partner and partner-to-CRYM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C9 grouped by CRYM-low versus CRYM-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYM→partner) and Y-score (partner→CRYM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR13C9 →	+0.012	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR13C9 by CRYM expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →