CRYL1

Across TCGA patient cohorts, CRYL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,573 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYL1-associated proteins across cancer lineages are COG3, SMC4, and ESD. Each is linked with CRYL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYL1-to-partner and partner-to-CRYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYL1 versus COG3 in UCEC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYL1→partner) and Y-score (partner→CRYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COG3 →	+0.382	+1.081	<.001	<.001	3	6
GBM	SMC4 →	-0.534	-0.369	<.001	.003	3	6
BRCA	ESD →	+0.321	+0.521	<.001	<.001	3	6
CCRCC	TOP2A_S1247 →	-0.824	-0.634	<.001	<.001	3	6
PDAC	NCL_S67 →	-0.976	-0.611	<.001	<.001	3	6
LUAD	PBLD →	+0.621	+0.430	.005	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,573 associations by consensus.

CRYL1 vs COG3 — UCEC

Explore this scatter interactively →