CRYBG1

Across TCGA patient cohorts, CRYBG1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYBG1-associated genes across cancer lineages are GPRASP1, TSPY26P, and CHRD. Each is linked with CRYBG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYBG1-to-partner and partner-to-CRYBG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBG1 versus GPRASP1 in GBM, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG1→partner) and Y-score (partner→CRYBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPRASP1 →	-0.688	-0.374	<.001	<.001	3	6
CCRCC	TSPY26P →	-0.812	-0.336	<.001	<.001	3	6
BRCA	CHRD →	-1.573	-0.579	<.001	<.001	3	6
LSCC	SERPINB1 →	+0.988	+0.541	<.001	<.001	3	6
LSCC	PLEK2 →	+0.939	+0.434	<.001	<.001	3	5
LUAD	FILIP1 →	-0.811	-0.605	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,571 associations by consensus.

CRYBG1 vs GPRASP1 — GBM

Explore this scatter interactively →