CRIP2

Across TCGA patient cohorts, CRIP2 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRIP2-associated genes across cancer lineages are PRR30, MIR3659, and SPCS2P2. Each is linked with CRIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRIP2-to-partner and partner-to-CRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR30 grouped by CRIP2-low versus CRIP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIP2→partner) and Y-score (partner→CRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRR30 →	+0.300	+4.009	.002	.001	3	2
UCEC	MIR3659 →	+0.357	+4.132	<.001	.009	3	1
UCEC	SPCS2P2 →	+0.152	+4.350	<.001	<.001	3	1
UCEC	OOEPP1 →	+0.285	+3.520	.001	.002	3	1
UCEC	OR6R2P →	+0.291	+3.383	.008	.003	3	1
UCEC	MLECP1 →	+0.105	+4.811	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

PRR30 by CRIP2 expression — UCEC

Explore this box plot interactively →