Q-omics provides the consensus-scored SPCS2P2 profile across patient tissues and cancer cell-line models. SPCS2P2 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, SPCS2P2 RNA expression shows 5,478 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where SPCS2P2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SPCS2P2 survival associations across molecular data types. SPCS2P2 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SPCS2P2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	KIRC (66)	view →

This table ranks reproducible SPCS2P2 RNA expression–survival associations across cancer types. High SPCS2P2 expression shows unfavorable associations in KIRC, READ, KICH, LUAD, PCPG and THCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .026). Together, the overview and detailed table identify KIRC as the clearest survival context for SPCS2P2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.290	0.645	.026	66	view →
READ	DFS	Tertile	IV	0.158	0.668	.001	51	view →
KICH	DFS	Tertile	II,III,IV	0.077	0.851	<.001	45	view →
LUAD	OS	Tertile	III,IV	0.181	0.672	<.001	36	view →
PCPG	OS	Tertile	All	0.786	0.963	<.001	36	view →
THCA	DFS	Tertile	II,III,IV	0.121	0.677	.017	27	view →

Pink = unfavorable, green = favorable. all 14 lineages →

SPCS2P2-KIRC (DFS)

Kaplan–Meier survival curve for SPCS2P2 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SPCS2P2 in patient tissues and cancer cell lines. In patient samples, SPCS2P2 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,478	STAD (5058)	view →
RNA	2,146	SARC (885)	view →