CREB1

Across TCGA patient cohorts, CREB1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,259 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CREB1-associated genes across cancer lineages are ACVR2A, CLK1, and USP44. Each is linked with CREB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CREB1-to-partner and partner-to-CREB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREB1 versus ACVR2A in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB1→partner) and Y-score (partner→CREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACVR2A →	+0.423	+0.226	.001	.001	3	3
CCRCC	CLK1 →	+0.361	+0.277	.001	<.001	3	3
OV	USP44 →	+0.616	+0.245	.001	<.001	3	3
LSCC	GCLM →	-0.963	-0.140	.002	<.001	3	3
CCRCC	HMOX1 →	+0.614	+0.215	.005	.003	3	2
COAD	CGRRF1 →	+0.501	+0.242	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

CREB1 vs ACVR2A — GBM

Explore this scatter interactively →