CRACR2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRACR2B mutation is significantly associated with the RNA expression of many other genes, with 959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRACR2B-associated genes across cancer lineages are UBTFL11, SNORA59B, and RN7SL248P. Each is linked with CRACR2B in more than 1 cancer types. Because this analysis shows association rather than direction, both CRACR2B-to-partner and partner-to-CRACR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBTFL11 grouped by CRACR2B-low versus CRACR2B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRACR2B→partner) and Y-score (partner→CRACR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADUBTFL11 →+0.042+4.321<.001.00232
CESCSNORA59B →+0.069+3.885.007.00732
CESCRN7SL248P →+0.096+6.000<.001<.00132
UCECNPLP1 →+0.214+2.265<.001<.00132
UCECRNU7-81P →+0.317+3.132<.001.00532
SKCMTRBV24OR9-2 →+0.290+5.328<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 959 associations by consensus.

UBTFL11 by CRACR2B expression — COAD

Box plot of UBTFL11 in CRACR2B-low vs CRACR2B-high samples in COAD.

Explore this box plot interactively →

Exploration